... (BHAs) like salicylic acid can be used first to “prep” the skin. Your email address will not be published. Then slather on a serum like The Ordinary Niacinamide 10% + Zinc 1%. My other concern is can i use more of the same product in a skin care routine. The addition of, Like UV radiation, visible light can also lead to the production of free radicals. (2002). For this reason, topical application of vitamin C is required to maintain sufficient skin levels of vitamin C, Vitamin E is the most important lipid-soluble antioxidant in tissue and is particularly abundant in the outermost layer of the skin (the stratum corneum) where it is delivered by sebum. Stallings, A. In fact, a large randomized controlled study found that the combination of niacinamide and NAG worked really well at reducing pigmentation. Manela-Azulay, M. & Bagatin, E. (2009). But how do we know which skincare ingredients work well together? We have already seen earlier how vitamin C and glycolic acid enhanced each others collagen-boosting effects when combined with centella asiatica. ‘Cosmeceuticals vitamins’. Does Hyaluronic Acid Cause Acne? In addition, AHAs increase the rate of skin cell turnover which helps bring skin pigment to the surface of the skin faster where it can be shed as part of normal epidermal desquamation (skin shedding) [46]. that is known to reduce pigmentation and inflammation and has anti-aging properties [43]. 12 Derm-Approved Drugstore Products To Try, The Only 4 Skincare Ingredients You Actually Need, What You Need to Know Before a Casual Hookup, What You Should Know Before You Say That Someone Looks 'Anorexic', A Top Derm Shares Her Pregnancy Skincare Routine, Things You Should Know BEFORE You Visit the Gyno. Hyaluronic acid and niacinamide are both water-based treatment and they can be used together. You might unknowingly undo them with a popular acne-fighting ingredient, benzoyl peroxide. Remember all those benefits from vitamin C? These effects are largely down to the polyphenols (antioxidant molecules) that are naturally present in green tea. Yet another example of more is more in skincare! In fact, vitamin C is the best-known stimulator of collagen production [35]. In fact, a large randomized controlled study found that the combination of niacinamide and NAG worked really well at reducing pigmentation. Farage, M., Miller, K., Elsner, P. & Maibach, H. (2013). Among ingredient MVPs, vitamin C tops the list. (1991). Laura is a skincare addict and sunscreen enthusiast with more than 10 years of experience working in healthcare and over 5 years of experience working as a nurse. Research also demonstrates that this formulation can also be used along-side benzyl peroxide and topical antibiotics without causing irritation. Furthermore, niacinamide appears to have an additive effect when combined with NAG. Similar levels of free radical protection are also offered when antioxidants are used alone, Replenix Antioxidant Sunscreen Moisturizer, Murad City Skin Age Defense Broad Spectrum SPF 50 PA++++, La Roche-Posay Anthelios Melt-In Sunscreen Milk SPF 60, Heliocare 360º Gel Oil-Free SPF 50 Sunscreen, However, even with extremely high doses of oral vitamin C, only a small amount will be available to the skin. Vitamin E returns the favor by increasing the action of vitamin C four-fold (4x) [19][20]. In order to get the maximum benefits from our skincare ingredients, we should look for products that contain the above combinations. Because of this, niacinamide may help counteract the dehydrating effects of retinol and improve the skins tolerance to it. Gycolic toner, pure L Absorbic Acid powder mix with a snail mucin and a Vit C serum (Andalou) with a Vit C E Ferulic oil?? Vitamin E is the most important lipid-soluble antioxidant in tissue and is particularly abundant in the outermost layer of the skin (the stratum corneum) where it is delivered by sebum. Haftek, M. Mac-Mary, S., Le Bitoux, M. et al. vitamin B3) comes in. This is because both vitamin C and glycolic acid are known to boost collagen levels in the skin and it appears that their effects may be additive. Specifically, 4% niacinamide combined with 2% NAG was significantly more effective at reducing pigmentation than a vehicle control formulation [64]. AHAs, such as glycolic and lactic acid, act as chemical exfoliants and help remove dead skin cells and loosen the top layer of skin. Farage, M., Miller, K., Elsner, P. & Maibach, H. (2008). Loden, M. (2016). Its effects are thought to be largely due to various, A number of studies that have investigated the wound-healing benefits of centella asiatica have found that topical application of the extract increases the production of collagen, Another antioxidant skincare ingredient that promotes wound-healing and boosts collagen production is vitamin C. For this reason, the combination of vitamin C and centella asiatica may lead to improved anti-oxidant, collagen-boosting, and wound-healing effects. AHAs, such as glycolic and lactic acid, act as chemical exfoliants and help remove dead skin cells and loosen the top layer of skin. ‘Caffeine’s mechanisms of action and its cosmetic use’. ‘Hydration effects on the barrier function of stratum corneum lipids: Raman analysis of ceramides 2, III and 5’. Davis, E. & Callender, V. (2010). Great for acne breakouts, salicylic acid shrinks them up, and fast. Ceramides account for about 45-50% of this mixture, cholesterol for approximately 25%, and free fatty acids for around 10-15% [25]. Some research suggests that caffeine enhances the antioxidant effects of green tea polyphenols and that both together may help prevent free radical production and UVB-induced skin cancer [23]. Lactic acid and salicylic acid are considered as a chemical exfoliant that will remove dead skin cells and improve skin texture. Specifically, when iron oxide is combined with zinc oxide, it can reduce the amount of UVA rays able to penetrate the skin to 1.5% [37]. A number of studies that have investigated the wound-healing benefits of centella asiatica have found that topical application of the extract increases the production of collagen [34]. “Our skin’s barrier relies on lipids to remain healthy, plump, and capable of holding in moisture,” Dr. Libby says. While all patients experienced reductions in hyperpigmentation, those who used the iron oxide sunscreen experiences significantly greater improvements, Murad City Skin Age Defense Broad-Spectrum SPF 50 PA++++, Skinceuticals UV Defense Broad-Spectrum SPF50 Physical Fusion Sunscreen, Tizo 3 Tinted Face Mineral SPF40 Sunscreen, Another great skincare ingredient combination for, Resveratrol is the potent antioxidant found in grapes (and red wine!) Although, resveratrol, alone, performed similarly well to the combination [47]. Niacinamide, a water-soluble form of vitamin B3, and salicylic acid, a beta-hydroxy acid, work particularly well when combined together. "Some work better layered while others need to be formulated together," she shares. They basically ‘mop-up’ the damage done by UV radiation and other environmental aging factors (smoking, pollution, etc.) Lowe, N. (2006). Thank you again. Laura is currently working in healthcare education and writes for ScienceBecomesHer in her spare time. As it’s so harsh on its own, it’s not a good idea to use it together with salicylic acid or retinoids. The Benefits Of Snail Mucin In Skin Care. ‘Anti-melanogenic effects of resveratryl triglycolate, a novel hybrid compound derived by esterification of resveratrol with glycolic acid’. Specifically, a mix of 0.5% ferulic acid and 1% vitamin E with 15% vitamin C increases the effects of vitamin C eight-fold (8x) [19]. Gohli, K., Patel, J. Glycolic acid, alone, boosted collagen production 2-fold (2x), 3-fold (3x) when combined with centella asiatica, and four-fold (4x) when combined with both vitamin C andcentella asiatica [35]. Golden, G., Guzek, D., Kennedy, A., McKie, J. Lol. ‘Practical uses of botanicals in skin care’. However, in certain formulas, the combination of glycolic acid and retinol can be well-tolerated and a complimentary and effective acne treatment. Usuki, A., Ohashi, A., Sato, H., Ochiai, Y., Ichihashi, M. & Funasaka, Y. Hashim, P. (2014). Lee, T., Seo, J., Baek, S. & Kim, S. (2014). ‘Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine’. When used together, vitamin C and glycolic acid demonstrated an ability to significantly improve hyperpigmentation, as well as reduce pore size and improve skin texture [54]. Parameshwaraiah, S. & Shivakumar, H. (1998). However, NAG can be unstable when used alone [62]. This combo is proof that too much of a good thing is a bad thing. ‘Irradiation of skin with visible light induced reactive oxygen species and matrix degrading enzymes’. Use a toner like La Roche-Posay’s Effaclar Clarifying Solution Acne Toner With Salicylic Acid. ‘The effect of glycolic acid on the treatment of acne in Asian skin’. ‘The inhibitory effect of glycolic acid and lactic acid on melanin synthesis in melanoma cells’. Lactic acid is a type of alpha hydroxy acid(AHA) while Salicylic acid is a type of beta-hydroxy acid(BHA). Products That Combine Retinol & Niacinamide: Although the combination of glycolic acid and vitamin C may not be suitable for all skin types, they make a powerful pairing. Thank you. ‘Human skin-depigmenting effects of resveratryl triglycolate, a hybrid compound of resveratrol and glycolic acid’. Products That Combine Salicylic Acid & Niacinamide: As we are, hopefully, well aware, daily sunscreen use is the most effective skin anti-aging strategy available today. When used together, they’re more likely to cause redness and irritations. & Lim, H. (2008). Why Is My Skin So Sensitive All Of A Sudden? Frederick, J., Snell, H. & Haywood, E. (1989) ‘Solar ultraviolet radiation at the earth’s surface’. When this lipid matrix is depleted, skin can become dehydrated [25] which results in rougher and duller looking skin. that is known to reduce pigmentation and inflammation and has anti-aging properties, It inhibits tyrosinase, the key enzyme in the production of melanin, in various ways and thus prevents the conversion of DOPA to melanin, Some research suggests that glycolic acid, as well as other AHAs, also inhibit tyrosinase, In addition, AHAs increase the rate of skin cell turnover which helps bring skin pigment to the surface of the skin faster where it can be shed as part of normal epidermal desquamation (skin shedding), In addition, glycolic acid is very good at penetrating skin, Recently, a hybrid of glycolic acid and resveratrol, resveratryl triglycolate, has demonstrated the ability to reduce sun induced pigmentation when applied twice daily for 6-8 weeks, When investigated separately, this combination of resveratrol and glycolic acid inhibited tyrosinase more effectively than glycolic acid alone. 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