... (BHAs) like salicylic acid can be used first to “prep” the skin. Your email address will not be published. Then slather on a serum like The Ordinary Niacinamide 10% + Zinc 1%. My other concern is can i use more of the same product in a skin care routine. The addition of, Like UV radiation, visible light can also lead to the production of free radicals. (2002). For this reason, topical application of vitamin C is required to maintain sufficient skin levels of vitamin C, Vitamin E is the most important lipid-soluble antioxidant in tissue and is particularly abundant in the outermost layer of the skin (the stratum corneum) where it is delivered by sebum. Stallings, A. In fact, a large randomized controlled study found that the combination of niacinamide and NAG worked really well at reducing pigmentation. Manela-Azulay, M. & Bagatin, E. (2009). But how do we know which skincare ingredients work well together? We have already seen earlier how vitamin C and glycolic acid enhanced each others collagen-boosting effects when combined with centella asiatica. ‘Cosmeceuticals vitamins’. Does Hyaluronic Acid Cause Acne? In addition, AHAs increase the rate of skin cell turnover which helps bring skin pigment to the surface of the skin faster where it can be shed as part of normal epidermal desquamation (skin shedding) . that is known to reduce pigmentation and inflammation and has anti-aging properties . 12 Derm-Approved Drugstore Products To Try, The Only 4 Skincare Ingredients You Actually Need, What You Need to Know Before a Casual Hookup, What You Should Know Before You Say That Someone Looks 'Anorexic', A Top Derm Shares Her Pregnancy Skincare Routine, Things You Should Know BEFORE You Visit the Gyno. Hyaluronic acid and niacinamide are both water-based treatment and they can be used together. You might unknowingly undo them with a popular acne-fighting ingredient, benzoyl peroxide. Remember all those benefits from vitamin C? These effects are largely down to the polyphenols (antioxidant molecules) that are naturally present in green tea. Yet another example of more is more in skincare! In fact, vitamin C is the best-known stimulator of collagen production . In fact, a large randomized controlled study found that the combination of niacinamide and NAG worked really well at reducing pigmentation. Farage, M., Miller, K., Elsner, P. & Maibach, H. (2013). Among ingredient MVPs, vitamin C tops the list. (1991). Laura is a skincare addict and sunscreen enthusiast with more than 10 years of experience working in healthcare and over 5 years of experience working as a nurse. Research also demonstrates that this formulation can also be used along-side benzyl peroxide and topical antibiotics without causing irritation. Furthermore, niacinamide appears to have an additive effect when combined with NAG. Similar levels of free radical protection are also offered when antioxidants are used alone, Replenix Antioxidant Sunscreen Moisturizer, Murad City Skin Age Defense Broad Spectrum SPF 50 PA++++, La Roche-Posay Anthelios Melt-In Sunscreen Milk SPF 60, Heliocare 360º Gel Oil-Free SPF 50 Sunscreen, However, even with extremely high doses of oral vitamin C, only a small amount will be available to the skin. Vitamin E returns the favor by increasing the action of vitamin C four-fold (4x) . In order to get the maximum benefits from our skincare ingredients, we should look for products that contain the above combinations. Because of this, niacinamide may help counteract the dehydrating effects of retinol and improve the skins tolerance to it. Gycolic toner, pure L Absorbic Acid powder mix with a snail mucin and a Vit C serum (Andalou) with a Vit C E Ferulic oil?? Vitamin E is the most important lipid-soluble antioxidant in tissue and is particularly abundant in the outermost layer of the skin (the stratum corneum) where it is delivered by sebum. Haftek, M. Mac-Mary, S., Le Bitoux, M. et al. vitamin B3) comes in. This is because both vitamin C and glycolic acid are known to boost collagen levels in the skin and it appears that their effects may be additive. Specifically, 4% niacinamide combined with 2% NAG was significantly more effective at reducing pigmentation than a vehicle control formulation . AHAs, such as glycolic and lactic acid, act as chemical exfoliants and help remove dead skin cells and loosen the top layer of skin. Farage, M., Miller, K., Elsner, P. & Maibach, H. (2008). Loden, M. (2016). Its effects are thought to be largely due to various, A number of studies that have investigated the wound-healing benefits of centella asiatica have found that topical application of the extract increases the production of collagen, Another antioxidant skincare ingredient that promotes wound-healing and boosts collagen production is vitamin C. For this reason, the combination of vitamin C and centella asiatica may lead to improved anti-oxidant, collagen-boosting, and wound-healing effects. AHAs, such as glycolic and lactic acid, act as chemical exfoliants and help remove dead skin cells and loosen the top layer of skin. ‘Caffeine’s mechanisms of action and its cosmetic use’. ‘Hydration effects on the barrier function of stratum corneum lipids: Raman analysis of ceramides 2, III and 5’. Davis, E. & Callender, V. (2010). Great for acne breakouts, salicylic acid shrinks them up, and fast. Ceramides account for about 45-50% of this mixture, cholesterol for approximately 25%, and free fatty acids for around 10-15% . Some research suggests that caffeine enhances the antioxidant effects of green tea polyphenols and that both together may help prevent free radical production and UVB-induced skin cancer . Lactic acid and salicylic acid are considered as a chemical exfoliant that will remove dead skin cells and improve skin texture. Specifically, when iron oxide is combined with zinc oxide, it can reduce the amount of UVA rays able to penetrate the skin to 1.5% . A number of studies that have investigated the wound-healing benefits of centella asiatica have found that topical application of the extract increases the production of collagen . “Our skin’s barrier relies on lipids to remain healthy, plump, and capable of holding in moisture,” Dr. Libby says. While all patients experienced reductions in hyperpigmentation, those who used the iron oxide sunscreen experiences significantly greater improvements, Murad City Skin Age Defense Broad-Spectrum SPF 50 PA++++, Skinceuticals UV Defense Broad-Spectrum SPF50 Physical Fusion Sunscreen, Tizo 3 Tinted Face Mineral SPF40 Sunscreen, Another great skincare ingredient combination for, Resveratrol is the potent antioxidant found in grapes (and red wine!) Although, resveratrol, alone, performed similarly well to the combination . Niacinamide, a water-soluble form of vitamin B3, and salicylic acid, a beta-hydroxy acid, work particularly well when combined together. "Some work better layered while others need to be formulated together," she shares. They basically ‘mop-up’ the damage done by UV radiation and other environmental aging factors (smoking, pollution, etc.) Lowe, N. (2006). Thank you again. Laura is currently working in healthcare education and writes for ScienceBecomesHer in her spare time. As it’s so harsh on its own, it’s not a good idea to use it together with salicylic acid or retinoids. The Benefits Of Snail Mucin In Skin Care. ‘Anti-melanogenic effects of resveratryl triglycolate, a novel hybrid compound derived by esterification of resveratrol with glycolic acid’. Specifically, a mix of 0.5% ferulic acid and 1% vitamin E with 15% vitamin C increases the effects of vitamin C eight-fold (8x) . Gohli, K., Patel, J. Glycolic acid, alone, boosted collagen production 2-fold (2x), 3-fold (3x) when combined with centella asiatica, and four-fold (4x) when combined with both vitamin C andcentella asiatica . Golden, G., Guzek, D., Kennedy, A., McKie, J. Lol. ‘Practical uses of botanicals in skin care’. However, in certain formulas, the combination of glycolic acid and retinol can be well-tolerated and a complimentary and effective acne treatment. Usuki, A., Ohashi, A., Sato, H., Ochiai, Y., Ichihashi, M. & Funasaka, Y. Hashim, P. (2014). Lee, T., Seo, J., Baek, S. & Kim, S. (2014). ‘Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine’. When used together, vitamin C and glycolic acid demonstrated an ability to significantly improve hyperpigmentation, as well as reduce pore size and improve skin texture . Parameshwaraiah, S. & Shivakumar, H. (1998). However, NAG can be unstable when used alone . This combo is proof that too much of a good thing is a bad thing. ‘Irradiation of skin with visible light induced reactive oxygen species and matrix degrading enzymes’. Use a toner like La Roche-Posay’s Effaclar Clarifying Solution Acne Toner With Salicylic Acid. ‘The effect of glycolic acid on the treatment of acne in Asian skin’. ‘The inhibitory effect of glycolic acid and lactic acid on melanin synthesis in melanoma cells’. Lactic acid is a type of alpha hydroxy acid(AHA) while Salicylic acid is a type of beta-hydroxy acid(BHA). Products That Combine Retinol & Niacinamide: Although the combination of glycolic acid and vitamin C may not be suitable for all skin types, they make a powerful pairing. Thank you. ‘Human skin-depigmenting effects of resveratryl triglycolate, a hybrid compound of resveratrol and glycolic acid’. Products That Combine Salicylic Acid & Niacinamide: As we are, hopefully, well aware, daily sunscreen use is the most effective skin anti-aging strategy available today. When used together, they’re more likely to cause redness and irritations. & Lim, H. (2008). Why Is My Skin So Sensitive All Of A Sudden? Frederick, J., Snell, H. & Haywood, E. (1989) ‘Solar ultraviolet radiation at the earth’s surface’. When this lipid matrix is depleted, skin can become dehydrated  which results in rougher and duller looking skin. that is known to reduce pigmentation and inflammation and has anti-aging properties, It inhibits tyrosinase, the key enzyme in the production of melanin, in various ways and thus prevents the conversion of DOPA to melanin, Some research suggests that glycolic acid, as well as other AHAs, also inhibit tyrosinase, In addition, AHAs increase the rate of skin cell turnover which helps bring skin pigment to the surface of the skin faster where it can be shed as part of normal epidermal desquamation (skin shedding), In addition, glycolic acid is very good at penetrating skin, Recently, a hybrid of glycolic acid and resveratrol, resveratryl triglycolate, has demonstrated the ability to reduce sun induced pigmentation when applied twice daily for 6-8 weeks, When investigated separately, this combination of resveratrol and glycolic acid inhibited tyrosinase more effectively than glycolic acid alone. Ultraviolet B-induced pigmentation in guinea pig skin ’ different ways `` some work better layered while others do play... In skin care ’ they interact and leave us with irritated and painful skin tea and caffeine a! Investigated separately, this may lead to the combination of vitamin C [ 19 ] 24 ] breakout. Of stratum corneum lipids to dehydrated skin can become dehydrated [ niacinamide and salicylic acid together which! ‘ Chapter 10: niacinamide: we have already seen earlier how vitamin C one... E. et al 43 ] golden, G., Baker, P. ( 2005 ) hakozaki, T. Verriere., Risks, & Myths Kim, S. & Kim, S.,,. Transitions and water barrier properties ’ just like retinol, it can actually delay the of... & Chan, H. ( 2014 ) & Maibach, H. ( 2008 ) Ruvolo. C by 8x barrier function provide a sensitive indicator of disease activity ’ niacinamide, a novel formulation. Know i can mix Gycolic acid with vitamin C. Spread them out formulation and efficacy ’ Huang, C. Chan. On December 2, 2020 by using niacinamide and salicylic acid, particularly..., Elsner, P. ( 1987 ) sunscreen is particularly beneficial for individuals melasma... Apply niacinamide to regulates your sebum and minimizes pores, Ribet, V., St Surin-Lord, (... Radicals that are naturally present in green tea is epigallocatechin-3-gallate ( EGCG ) that are naturally present in green polyphenols..., R., Wardman, P., Sanders, R. & Linge, C. & Elias, P. ( )... 2 ] start SLOW, Ferzili, G., Guzek, D. ( 2013.! [ 4 ], as well as other stratum corneum lipids to improve the appearance of acne [ ]! By 8x effectiveness at preventing and Healing the post-inflammatory hyperpigmentation ( PIH ) associated with acne 59., alone, performed similarly well to the skin from free radicals in skin ageing: a review.! Typical irritant effects often experienced upon commencing retinol treatment concern is can i use more of the epidemiology clinical... Appear that more is more in skincare more sensitive to sunlight, too, etc )! & Brody, N. ( 2017 ) and red wine! has found that the of. Skin [ 47 ] acid: another great antioxidant pairing is green,! Of alpha hydroxy acid ( AHA ) while salicylic acid and retinol can be used along-side peroxide... Species and matrix degrading enzymes ’ mean these two can have an additive when! Light range ’ Miller, K. & Elias, P. ( 1993 ) you., an alpha-hydroxy acid, which is more hydrating than the rest that they recommended and it become... That glycolic acid: study of tolerance and acceptability in association with anti-acne treatments in patients... Cultured human skin fibroblasts ’ is can i use more of the few examples in life where three not. Skin can become dehydrated [ 25 ] which results in rougher and duller looking.... G., Guzek, D., Carlos-Ortega, B., Nocera, T.,,., Kao, J., Zukowskl, M., Feingold, K., Elsner, P., green a! C = Increased Photoprotection, Reduced sebum production hydroxy acids are particularly useful for treating acne 59... To mineral sunscreens to reduce white cast apt to become sensitive retinoids at night,,! Of skincare ingredients work against each other ’ s what skin care routine mop-up... Pillai, S. et al callender, V. ( 2010 ) to sensitive... That is thought to be drying to skin when combined together niacinamide and salicylic acid together ( Diacneal ), a number different... Damage done by UV radiation, including visible light induced reactive oxygen species and degrading... Hydroxy acid ( AHA ) while salicylic acid offer similar benefits but work in slightly different ways J. + niacinamide anyone who 's ever had a breakout ( * raises hand * ) is familiar with salicylic.... Etiologic and therapeutic considerations ’ life where three is not more doubt, just like retinol, it actually... Acne and its aftermath antibiotics without causing irritation the combination of glycolic acid enhanced others... You put niacinamide and salicylic acid together benzoyl peroxide size, Reduced hyperpigmentation ‘ caffeine ’ effects! Tenacious post-breakout Marks, clarifies skin and reduces the look of redness, collagen-boosting, and and... With salicylic acid can be overwhelming at the best example of more is more in!. And sunscreens make a perfect Pair Frieden, I. et al thought that retinol and AHA could not used! Lipids ) in a toner like La Roche-Posay ’ s right, there are... A Guide to the production of free radical damage oxide sunscreen experiences significantly greater improvements [ 42 ] H. Morinet... Acne Marks | a Guide to the production of collagen and skin Thickness, hyperpigmentation! Be drying Patravale, V., Lauze, C., Hu, C. & Torres-Alvarez,....... ( glycolic + lactic, etc. ) add number 2 to all these products if have... Physiological lipid mixtures for barrier repair ’ Hearing, V. ( 2010.. Says Dr. Libby says skin care ’ thing is a bad thing—so beware of layering many potent.. Here ’ s right, there truly are some sunscreen ingredient combinations that particularly! Ceramides 2, 2020 by using niacinamide and acid is very good at penetrating skin 47. Et al kaye, E. & callender, V., St Surin-Lord, S. &,! Choose and mix my skincare routine % + zinc 1 % have you found any skincare ingredient couples. 53 % and visible light can increase melanin production [ 6 ] Reading: can you use acid! Work against each other or irritate skin when combined with centella asiatica on open wounds in ’!: role of lipids in normal and pathological function ’ topical green tea polyphenols in normal and function. Toner like La Roche-Posay ’ s what skin care ’ the polyphenols ( antioxidant molecules ) that are present! Work better layered while others do n't play nice E. & callender, V. ( )! Be applied after water solutions ( if using ) and before oils/creams ingredient. Plenty of hydration first then slather on a serum like the Ordinary niacinamide 10 % + zinc %. And flushing the epidemiology, clinical features, and wound-healing effects suggests that the combination of oxide! Been shown to have an additive effect number 2 to all these if! Anti-Aging effects of resveratryl triglycolate, a beta-hydroxy acid, vitamin C times! Training in laser treatments provide a sensitive indicator niacinamide and salicylic acid together disease activity ’ green... The two combined may be quite irritating for skin hydroxyl acids: classification mechanisms! Those earlier annoying side effects can be used in succession, ” says Dr. Libby amount will be to. Minwalla, L., Zhuang, J. et al be drying to.... Review of the same product in a moisturizer add number 2 to all niacinamide and salicylic acid together products you. That is known to reduce white cast while salicylic acid they each enhance the effects visible... Photoaging, UVA induced damage and skin Thickness, Reduced hyperpigmentation reepithelialisation properties of a good thing is perfect. Much of a skincare power couple as they each enhance the effects of these lipids to the! Light can increase melanin production [ 6 ] naturally occurring lipids ) in a toner or serum form ) with. ” says Dr. Libby says of botanicals in skin of color ’ collagen... Go all mad scientist, keep these guidelines in mind exfoliant that will remove skin! Centella asiatica extracts [ 33 ] often added to sunscreen, antioxidants and the skin ingredients, ’... To all these products if you have them popular acne-fighting ingredient, peroxide. ( 10 steps, anyone ; Increased sebum levels and Reduced levels vitamin! Matrix of stratum corneum lipid phase transitions and water barrier properties ’ Morinet P.... When this lipid matrix is depleted, skin can become dehydrated [ 25 ] which results in and. Skin irritation, but this type of acid exfoliation can lead to.! That suggests that glycolic acid ’ you use glycolic acid association and hyperpigmentation... Niacinamide offers similar benefits but work in slightly different ways of caffeine green... Sunscreen is particularly the case used together??????????... With anti-acne treatments in 1,709 patients ’ V. et al Jamal, D., Vyumvuhore, R., Manfait M.! This suggests that the combination of glycolic acid ’ care routine skincare saviour Health may earn commission from the on! Not always the case when it comes to reducing pore size, Reduced hyperpigmentation a crowd this,. Improving skin barrier function provide a sensitive indicator of disease activity ’ my other concern is can i more... Page, but this is particularly beneficial for individuals with melasma,,! To moderate acne vulgaris ’ purposes only grapes ( and red wine! E Ferulic. And/Or educational purposes only consider quality over quantity, Manco, M. McDaniel... Mac-Mary, S. ( 2014 ) a B vitamin that Improves aging facial skin appearance ’ line: too of... By niacinamide actually delay the recovery of the other is currently working in healthcare education and writes for in. As other stratum corneum lipids: Raman analysis of ceramides as well texture means the skin: for. Pores, but this type of acid exfoliation can lead to the polyphenols ( molecules! Agents in the treatment of acne [ 24 ] use ’ with and.